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- AMPL
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dask
1247 IssuesParallel computing with task scheduling
(dask/dask)electrum
1210 IssuesElectrum Bitcoin Wallet
(spesmilo/electrum)staged-recipes
1208 IssuesA place to submit conda recipes before they become fully fledged conda-forge feedstocks
(conda-forge/staged-recipes)vision
1199 IssuesDatasets, Transforms and Models specific to Computer Vision
(pytorch/vision)paramiko
1161 IssuesThe leading native Python SSHv2 protocol library.
(paramiko/paramiko)panel
1159 IssuesPanel: The powerful data exploration & web app framework for Python
(holoviz/panel)qiskit
1157 IssuesQiskit is an open-source SDK for working with quantum computers at the level of extended quantum circuits, operators, and primitives.
(qiskit/qiskit)boto
1119 IssuesFor the latest version of boto, see https://github.com/boto/boto3 -- Python interface to Amazon Web Services
(boto/boto)diffusers
1106 Issuesπ€ Diffusers: State-of-the-art diffusion models for image, video, and audio generation in PyTorch.
(huggingface/diffusers)pip
1058 IssuesThe Python package installer
(pypa/pip)lightning
1000 IssuesDeep learning framework to train, deploy, and ship AI products Lightning fast.
(lightning-ai/lightning)pytorch-lightning
1000 IssuesThe lightweight PyTorch wrapper for high-performance AI research. Scale your models, not the boilerplate.
(pytorchlightning/pytorch-lightning)wagtail
994 IssuesA Django content management system focused on flexibility and user experience
(wagtail/wagtail)pytest
986 IssuesThe pytest framework makes it easy to write small tests, yet scales to support complex functional testing
(pytest-dev/pytest)langflow
954 IssuesLangflow is a low-code app builder for RAG and multi-agent AI applications. Itβs Python-based and agnostic to any model, API, or database.
(langflow-ai/langflow)python
952 IssuesAll Algorithms implemented in Python
(thealgorithms/python)openlibrary
915 IssuesOne webpage for every book ever published!
(internetarchive/openlibrary)ranger
914 IssuesA VIM-inspired filemanager for the console
(ranger/ranger)scikit-image
896 IssuesImage processing in Python
(scikit-image/scikit-image)bokeh
876 IssuesInteractive Data Visualization in the browser, from Python
(bokeh/bokeh)mmsegmentation
868 IssuesOpenMMLab Semantic Segmentation Toolbox and Benchmark.
(open-mmlab/mmsegmentation)prefect
859 IssuesPrefect is a workflow orchestration framework for building resilient data pipelines in Python.
(prefecthq/prefect)osintgram
858 IssuesOsintgram is a OSINT tool on Instagram. It offers an interactive shell to perform analysis on Instagram account of any users by its nickname
(datalux/osintgram)ckan
850 IssuesCKAN is an open-source DMS (data management system) for powering data hubs and data portals. CKAN makes it easy to publish, share and use data. It powers catalog.data.gov, open.canada.ca/data, data.humdata.org among many other sites.
(ckan/ckan)coala
836 Issuescoala provides a unified command-line interface for linting and fixing all your code, regardless of the programming languages you use.
(coala/coala)face_recognition
832 IssuesThe world's simplest facial recognition api for Python and the command line
(ageitgey/face_recognition)adk-python
818 IssuesAn open-source, code-first Python toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.
(google/adk-python)penny-dreadful-tools
812 IssuesA suite of tools for the pdmtgo community
(pennydreadfulmtg/penny-dreadful-tools)ansible
799 IssuesAnsible is a radically simple IT automation platform that makes your applications and systems easier to deploy and maintain. Automate everything from code deployment to network configuration to cloud management, in a language that approaches plain English
(ansible/ansible)celery
775 IssuesDistributed Task Queue (development branch)
(celery/celery)redash
754 IssuesMake Your Company Data Driven. Connect to any data source, easily visualize, dashboard and share your data.
(getredash/redash)community.general
751 IssuesAnsible Community General Collection
(ansible-collections/community.general)modin
710 IssuesModin: Scale your Pandas workflows by changing a single line of code
(modin-project/modin)jarvis-on-messenger
710 Issues:speech_balloon: A community-driven python bot that aims to be as simple as possible to serve humans with their everyday tasks
(swapagarwal/jarvis-on-messenger)theano
699 IssuesTheano is a Python library that allows you to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficiently. It can use GPUs and perform efficient symbolic differentiation.
(theano/theano)coala-bears
694 IssuesBears for coala
(coala/coala-bears)beets
691 Issuesmusic library manager and MusicBrainz tagger
(beetbox/beets)pyvista
667 Issues3D plotting and mesh analysis through a streamlined interface for the Visualization Toolkit (VTK)
(pyvista/pyvista)mne-python
643 IssuesMNE : Magnetoencephalography (MEG) and Electroencephalography (EEG) in Python
(mne-tools/mne-python)scrapy
637 IssuesScrapy, a fast high-level web crawling & scraping framework for Python.
(scrapy/scrapy)beacon-skill
635 IssuesBeacon - agent-to-agent pings with optional RTC value attached (BoTTube/Moltbook/RustChain + UDP bus)
(scottcjn/beacon-skill)conda
628 IssuesA system-level, binary package and environment manager running on all major operating systems and platforms.
(conda/conda)tqdm
612 Issues:zap: A Fast, Extensible Progress Bar for Python and CLI
(tqdm/tqdm)marimo
609 IssuesA reactive notebook for Python β run reproducible experiments, execute as a script, deploy as an app, and version with git.
(marimo-team/marimo)aiida-core
606 IssuesThe official repository for the AiiDA code
(aiidateam/aiida-core)warehouse
599 IssuesThe Python Package Index
(pypi/warehouse)rustchain
591 IssuesProof-of-Antiquity blockchain β vintage PowerPC hardware earns 2.5x mining rewards. Hardware fingerprinting, Solana bridge (wRTC), AI agent economy. Discord: https://discord.gg/VqVVS2CW9Q
(scottcjn/rustchain)pygments
585 IssuesPygments is a generic syntax highlighter written in Python
(pygments/pygments)satpy
567 IssuesPython package for earth-observing satellite data processing
(pytroll/satpy)scanpy
562 IssuesSingle-cell analysis in Python. Scales to >1M cells.
(scverse/scanpy)