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bleachbit
309 IssuesBleachBit system cleaner for Windows and Linux
(bleachbit/bleachbit)hydra
307 IssuesHydra is a framework for elegantly configuring complex applications
(facebookresearch/hydra)autokey
302 IssuesAutoKey, a desktop automation utility for Linux and X11.
(autokey/autokey)antenna
300 IssuesAn online toolset to manage and analyze data collected from insect camera traps for research and conservation efforts.
(rolnicklab/antenna)nltk
299 IssuesNLTK Source
(nltk/nltk)black
295 IssuesThe uncompromising Python code formatter
(psf/black)mackup
293 IssuesKeep your application settings in sync (OS X/Linux)
(lra/mackup)red-discordbot
290 IssuesA multifunction Discord bot
(cog-creators/red-discordbot)borg
287 IssuesDeduplicating archiver with compression and authenticated encryption.
(borgbackup/borg)bottle
283 Issuesbottle.py is a fast and simple micro-framework for python web-applications.
(bottlepy/bottle)plomino
279 IssuesPowerful and flexible web-based application builder
(plomino/plomino)mmpretrain
271 IssuesOpenMMLab Pre-training Toolbox and Benchmark
(open-mmlab/mmpretrain)optimum
271 Issues🚀 Accelerate training and inference of 🤗 Transformers and 🤗 Diffusers with easy to use hardware optimization tools
(huggingface/optimum)superagi
267 Issues<⚡️> SuperAGI - A dev-first open source autonomous AI agent framework. Enabling developers to build, manage & run useful autonomous agents quickly and reliably.
(transformeroptimus/superagi)copyparty
267 IssuesPortable file server with accelerated resumable uploads, dedup, WebDAV, FTP, TFTP, zeroconf, media indexer, thumbnails++ all in one file, no deps
(9001/copyparty)lutris
264 IssuesLutris desktop client in Python / PyGObject
(lutris/lutris)sqlmesh
260 IssuesEfficient data transformation and modeling framework that is backwards compatible with dbt.
(tobikodata/sqlmesh)yournextrepresentative
260 Issues👥 A website for crowd-sourcing structured election candidate data
(democracyclub/yournextrepresentative) (microsoft/taskmatrix)taskmatrix
259 Issuesversatile-data-kit
257 IssuesOne framework to develop, deploy and operate data workflows with Python and SQL.
(vmware/versatile-data-kit)gradio
257 IssuesBuild and share delightful machine learning apps, all in Python. 🌟 Star to support our work!
(gradio-app/gradio) (deepseek-ai/deepseek-v3)deepseek-v3
256 Issuesgpy
256 IssuesGaussian processes framework in python
(sheffieldml/gpy)aeon
255 IssuesA toolkit for machine learning from time series
(aeon-toolkit/aeon)sunpy
253 IssuesSunPy - Python for Solar Physics
(sunpy/sunpy)augur
252 IssuesPipeline components for real-time phylodynamic analysis
(nextstrain/augur)prisma-client-py
252 IssuesPrisma Client Python is an auto-generated and fully type-safe database client designed for ease of use
(robertcraigie/prisma-client-py)bandit
250 IssuesBandit is a tool designed to find common security issues in Python code.
(pycqa/bandit)cppcoreguidelines
250 IssuesThe C++ Core Guidelines are a set of tried-and-true guidelines, rules, and best practices about coding in C++
(isocpp/cppcoreguidelines)proselint
248 IssuesA linter for prose.
(amperser/proselint)pdfminer
243 IssuesPython PDF Parser (Not actively maintained). Check out pdfminer.six.
(euske/pdfminer)investpy
243 IssuesFinancial Data Extraction from Investing.com with Python
(alvarobartt/investpy)investpy
243 Issuesinvestpy — is a Python library for historical data extraction from the spanish stock market
(alvarob96/investpy)saleor
241 IssuesSaleor Core: the high performance, composable, headless commerce API.
(saleor/saleor)drf-yasg
240 IssuesAutomated generation of real Swagger/OpenAPI 2.0 schemas from Django REST Framework code.
(axnsan12/drf-yasg)simple-salesforce
239 IssuesA very simple Salesforce.com REST API client for Python
(simple-salesforce/simple-salesforce)puddletag
237 IssuesPowerful, simple, audio tag editor for GNU/Linux
(puddletag/puddletag)beancount
230 IssuesBeancount: Double-Entry Accounting from Text Files.
(beancount/beancount)torchgeo
228 IssuesTorchGeo: datasets, samplers, transforms, and pre-trained models for geospatial data
(microsoft/torchgeo)requests
228 IssuesPython HTTP Requests for Humans™ ✨🍰✨
(requests/requests)requests
228 IssuesA simple, yet elegant HTTP library.
(psf/requests)vintageous
227 IssuesVi/Vim emulation for Sublime Text 3
(guillermooo/vintageous)num2words
226 IssuesModules to convert numbers to words. 42 --> forty-two
(savoirfairelinux/num2words)tornado
225 IssuesTornado is a Python web framework and asynchronous networking library, originally developed at FriendFeed.
(tornadoweb/tornado)mypaint
225 IssuesMyPaint is a simple drawing and painting program that works well with Wacom-style graphics tablets.
(mypaint/mypaint)seaborn
225 IssuesStatistical data visualization in Python
(mwaskom/seaborn)eventlet
223 IssuesConcurrent networking library for Python
(eventlet/eventlet)aiohttp
221 IssuesAsynchronous HTTP client/server framework for asyncio and Python
(aio-libs/aiohttp)django-ninja
216 Issues💨 Fast, Async-ready, Openapi, type hints based framework for building APIs
(vitalik/django-ninja)netbox
215 IssuesThe premier source of truth powering network automation. Open source under Apache 2. Public demo: https://demo.netbox.dev
(netbox-community/netbox)