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sopel
156 Issues:robot::speech_balloon: An easy-to-use and highly extensible IRC Bot framework. Formerly Willie.
(sopel-irc/sopel)pipenv
155 IssuesPython Development Workflow for Humans.
(pypa/pipenv)pytables
154 IssuesA Python package to manage extremely large amounts of data
(pytables/pytables)backintime
153 IssuesBack In Time - An an easy-to-use backup tool for GNU Linux using rsync in the back
(bit-team/backintime)evennia
152 IssuesPython MUD/MUX/MUSH/MU* development system
(evennia/evennia)altair
151 IssuesDeclarative statistical visualization library for Python
(altair-viz/altair)freezegun
151 IssuesLet your Python tests travel through time
(spulec/freezegun)rasterio
149 IssuesRasterio reads and writes geospatial raster datasets
(rasterio/rasterio)bpython
147 Issuesbpython - A fancy curses interface to the Python interactive interpreter
(bpython/bpython)nix.dev
147 IssuesAn opinionated guide for developers wanting to get things done with the Nix ecosystem.
(nixos/nix.dev)rasa
145 Issues💬 Open source machine learning framework to automate text- and voice-based conversations: NLU, dialogue management, connect to Slack, Facebook, and more - Create chatbots and voice assistants
(rasahq/rasa)rasa_nlu
145 Issuesturn natural language into structured data
(rasahq/rasa_nlu)pytext
145 IssuesA natural language modeling framework based on PyTorch
(facebookresearch/pytext)flask-admin
144 IssuesSimple and extensible administrative interface framework for Flask
(flask-admin/flask-admin)kivy-designer
142 IssuesUI designer for Kivy - DEPRECATED
(kivy/kivy-designer)zenml
141 IssuesZenML 🙏: Build portable, production-ready MLOps pipelines. https://zenml.io.
(zenml-io/zenml)pretix
141 IssuesTicket shop application for conferences, festivals, concerts, tech events, shows, exhibitions, workshops, barcamps, etc.
(pretix/pretix)cirq
141 IssuesA python framework for creating, editing, and invoking Noisy Intermediate Scale Quantum (NISQ) circuits.
(quantumlib/cirq)detect-secrets
141 IssuesAn enterprise friendly way of detecting and preventing secrets in code.
(yelp/detect-secrets)paperwork
140 IssuesPersonal document manager (Linux/Windows) -- Moved to Gnome's Gitlab
(openpaperwork/paperwork)pwntools
134 IssuesCTF framework and exploit development library
(gallopsled/pwntools)mpf
134 IssuesMission Pinball Framework: Open source software to run a real pinball machine.
(missionpinball/mpf)gevent
133 IssuesCoroutine-based concurrency library for Python
(gevent/gevent)supervision
132 IssuesWe write your reusable computer vision tools. 💜
(roboflow/supervision)web3.py
132 IssuesA python interface for interacting with the Ethereum blockchain and ecosystem.
(ethereum/web3.py)tensornetwork
131 IssuesA library for easy and efficient manipulation of tensor networks.
(google/tensornetwork)learning-object-oriented-python
130 IssuesThis repository walks you through the Object Oriented Programming in python. Illustrates real world examples, working codes and going about finding a coding solution.
(josharsh/learning-object-oriented-python)personfinder
129 IssuesPerson Finder is a searchable missing person database written in Python and hosted on App Engine.
(google/personfinder)scapy
128 IssuesScapy: the Python-based interactive packet manipulation program & library. Supports Python 2 & Python 3.
(secdev/scapy)autopep8
127 IssuesA tool that automatically formats Python code to conform to the PEP 8 style guide.
(hhatto/autopep8)httpretty
126 IssuesIntercept HTTP requests at the Python socket level. Fakes the whole socket module
(gabrielfalcao/httpretty)isort
124 IssuesA Python utility / library to sort imports.
(pycqa/isort)plover
124 IssuesOpen source stenotype engine
(openstenoproject/plover)mentorship-backend
124 IssuesMentorship System is an application that matches women in tech to mentor each other, on career development, through 1:1 relations during a certain period of time. This is the backend of this system.
(anitab-org/mentorship-backend)sdk-python
124 IssuesTemporal Python SDK
(temporalio/sdk-python)jarvis
123 IssuesPersonal Assistant for Linux and macOS
(sukeesh/jarvis)django-compressor
122 IssuesCompresses linked and inline javascript or CSS into a single cached file.
(django-compressor/django-compressor)pyrit
120 IssuesThe Python Risk Identification Tool for generative AI (PyRIT) is an open source framework built to empower security professionals and engineers to proactively identify risks in generative AI systems.
(azure/pyrit)malwaredatabase
118 IssuesThis repository is one of a few malware collections on the GitHub.
(endermanch/malwaredatabase)alembic
113 IssuesA database migrations tool for SQLAlchemy.
(sqlalchemy/alembic)buildozer
112 IssuesGeneric Python packager for Android and iOS
(kivy/buildozer)bump2version
112 IssuesVersion-bump your software with a single command
(c4urself/bump2version)devguide
111 IssuesThe Python developer's guide
(python/devguide)graphene
111 IssuesGraphQL framework for Python
(graphql-python/graphene) (deepseek-ai/deepseek-v3)deepseek-v3
110 Issuesqeda
110 IssuesQuantum electronic design automation software for optical circuits
(spooky-manufacturing/qeda)faststream
110 IssuesFastStream is a powerful and easy-to-use Python framework for building asynchronous services interacting with event streams such as Apache Kafka, RabbitMQ, NATS and Redis.
(airtai/faststream)lnldb
110 IssuesGetting rid of that 12+ y.o. perl mess.
(wpi-lnl/lnldb)six
109 IssuesPython 2 and 3 compatibility library
(benjaminp/six)haystack
109 Issues:mag: LLM orchestration framework to build customizable, production-ready LLM applications. Connect components (models, vector DBs, file converters) to pipelines or agents that can interact with your data. With advanced retrieval methods, it's best suited
(deepset-ai/haystack)